RegulonDB Summary History
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2006 |
Jan 2007 release 5.6 |
Jun 2007 release 5.7 |
Sep 2007 release 5.8 |
Jan 2008 release 6.0
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Apr 2008 release 6.1
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Jul 2008 release 6.2
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Jun 2009 *release 6.3 |
Jun 2009
release 6.4
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Mar 2010 release 6.7 |
Aug 2010 release 6.8 | Jan 2011 release 7.0 | May 2011 release 7.2 | Nov 2011 release 7.3 | March 2012 release 7.4 | August 2012 release 7.5 | December 2012 release 8.1 | April 2013 release 8.2 | Jun 2013 release 8.3 | Nov 2013 release 8.5 | April 2014 release 8.6 | February 2015 release 8.7 | May 2015 release 8.8 | Sep 2015 release 9.0 | April 2016 release 9.1 | Sep 2016 release 9.2 | February 2017 release 9.3 | May 2017 release 9.4 | Jun 2018 release 10.0 | Jul 2019 release 10.6 | May 2020 release 10.7 | Oct 2020 release 10.8 | April 2021 release 10.9 | December 2022 release 11.1 |
Regulons |
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387 | 397 | 401 | 416 | 426 | 438 | 439 | 447 | 453 | 455 | 456 | 460 | 469 | 475 | 475 | 479 | 480 | 480 | 488 | 493 | 537 | 540 | 544 | 549 | 556 |
Regulatory Interactions |
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2594 | 2644 | 2697 | 2767 | 2894 | 2954 | 3002 | 3055 | 3088 | 3112 | 3122 | 3148 | 3177 | 3195 | 3195 | 3231 | 3239 | 3239 | 3277 | 3355 | 3466 | 3473 | 3493 | 3937 | 3952 |
small RNA Interactions |
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51 | 51 | 203 | 203 | 202 | 202 | 219 | 227 | 227 | 227 | 227 | 227 | 227 | 227 | 227 | 222 | 224 | 224 | 224 | 235 | 235 | 235 | 235 | 242 | 247 |
Functional conformation of Transcriptional Regulators |
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233 | 235 | 232 | 238 | 238 | 241 | 243 | 352 | 355 | 356 | 355 | 356 | 357 | 358 | 358 | 363 | 365 | 365 | 370 | 378 | 383 | 408 | 409 | 410 | 420 | |||
Effectors |
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77 | 75 | 76 | 74 | 73 | 73 | 74 | 122 | 122 | 121 | 122 | 122 | 122 | 122 | 122 | 122 | 124 | 124 | 124 | 131 | 137 | 134 | 134 | 134 | 138 |
Transcriptional Factors |
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176 | 175 | 177 | 179 | 188 | 190 | 185 | 188 | 201 | 202 | 202 | 202 | 203 | 204 | 204 | 208 | 208 | 208 | 213 | 215 | 217 | 220 | 220 | 221 | 229 |
TFs Binding Sites |
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1861 | 1894 | 1940 | 1988 | 2037 | 2093 | 2109 | 2155 | 2184 | 2196 | 2214 | 2214 | 2241 | 2253 | 2253 | 2280 | 2285 | 2285 | 2320 | 2833 | 3020 | 6624 | 5912 | 6916 | 4147 | ||
Promoters |
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1840 | 1863 | 1878 | 1897 | 3736 | 3747 | 3754 | 8547 | 8550 | 8550 | 8551 | 8555 | 8580 | 8583 | 8583 | 8597 | 8597 | 8597 | 8605 | 8615 | 8623 | 8660 | 8663 | 8791 | 8795 |
Genes |
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4605 | 4605 | 4621 | 4622 | 4635 | 4635 | 4634 | 4637 | 4637 | 4639 | 4640 | 4639 | 4641 | 4641 | 4641 | 4650 | 4652 | 4652 | 4679 | 4694 | 4686 | 4732 | 4745 | 4708 | 4736 |
Transcription units |
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3386 | 3397 | 3409 | 3422 | 4463 | 4472 | 4477 | 4490 | 4505 | 4509 | 4510 | 4522 | 3538 | 3541 | 3541 | 3549 | 3547 | 3547 | 3556 | 3560 | 3553 | 3597 | 3599 | 3705 | 3696 |
Terminators |
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228 | 234 | 240 | 244 | 246 | 247 | 249 | 251 | 252 | 258 | 259 | 261 | 273 | 274 | 274 | 279 | 280 | 280 | 282 | 306 | 360 | 361 | 361 | 366 | 366 | ||
RBSs - Shine-Dalgarno |
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179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | 179 | ||
Attenuators |
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751 | 751 | 751 | 751 | 751 | 751 | 748 | 751 | 751 | 751 | 752 | 752 | 752 | 752 | 752 | 752 | 752 | 752 | 752 | 752 | 752 | 540 | 751 | 751 | 751 | |||||||||
Riboswitches |
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20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 51 | 51 | 51 | 51 | 51 | 51 | 51 | 51 | 51 | |||||||||
Product: |
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RNAs |
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114 | 114 | 114 | 114 | 114 | 114 | 216 | 227 | 227 | 218 | 219 | 219 | 220 | 221 | 221 | 231 | 233 | 233 | 222 | 108 | 203 | |||||||
small RNAs |
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81 | 81 | 92 | 92 | 109 | 94 | 108 | 108 | 108 | 110 | 111 | 111 | 111 | 113 | 113 | 113 | 125 | 125 | 114 | 117 | 116 | 120 | 132 | 94 | 111 | ||
Polypetides |
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4396 | 4509 | 4432 | 4432 | 4314 | 4442 | 4463 | 4358 | 4358 | 4358 | 4358 | 4358 | 4359 | 4358 | 4358 | 4356 | 4587 | 4353 | 4355 | 4340 | 4378 | 4419 | 4420 | 4432 | |
External References4 |
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4187 | 4274 | 4274 | 4336 | 4336 | 4596 | 4667 | 4880 | 5021 | 5096 | 5156 | 5398 | 5803 | 6008 | 6008 | 6581 | 6814 | 7122 | 7357 | 14477 | 15187 | 15715 | 9682 | 10174 | 10979 |
Synonyms |
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21399 | 16994 | 20865 | 20918 | 16732 | 16870 | 16946 | 17158 | 17203 | 17155 | 17336 | 12308 | 12483 | 12607 | 12607 | 12647 | 12898 | 17415 | 18473 | 24467 | 30226 | 30456 | 30574 | 30609 | 30794 | |
Functional Classes |
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5721 | 5800 | 5914 | 6042 | 6357 | 6448 | 6543 | 6813 | 6970 | 7139 | 7211 | 7248 | 7476 | 7594 | 7594 | 7788 | 7956 | 8035 | 8254 | 8349 | 8520 | 9461 | 8641 | 8698 | 8858 | ||||||||
Gensor Units | 50 | 50 | 51 | 51 | 51 | 51 | 51 | 51 | 51 | 53 | 53 | 53 | 53 | 53 | 53 | 53 | 53 | 53 | 53 | 53 | 53 | 53 | 53 | 53 |
1Only the active conformations.3Previously, there was a list of 180 transcriptional regulators experimentally determined (with 244 associated functional conformations), but as 27 of these putative regulators have no regulatory interaction known they were deleted, leaving only 153 known regulators. In addition there are 158 computationally predicted, making a total of 311 estimated regulators.
2 From the total 322 transcriptional DNA-binding regulators, 180 have experimental evidence and the rest are computationally predicted based on their helix-turn-helix DNA binding motif.
4Only PUBMED references