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ZraR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
zraSR_mRNA ZraP HydH zraSR zraP phosphate zraP_mRNA ZraR ZraS ZraR phosphate


Gensor Unit       
Name: ZraR
Signal name: High concentrations of zinc or lead.
Classification:
Groups: Posttranslational modification, protein turnover, chaperones
Signal transduction mechanisms
Gene Ontology Terms (GO): biological_process GO:0071284 - cellular response to lead ion
GO:0071294 - cellular response to zinc ion
GO:0018106 - peptidyl-histidine phosphorylation
GO:0000160 - phosphorelay signal transduction system
GO:0016310 - phosphorylation
GO:0046777 - protein autophosphorylation
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cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0005622 - intracellular anatomical structure
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
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molecular_function GO:0005524 - ATP binding
GO:0003677 - DNA binding
GO:0050897 - cobalt ion binding
GO:0005507 - copper ion binding
GO:0016301 - kinase activity
GO:0016151 - nickel cation binding
GO:0000166 - nucleotide binding
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Components:
  Function Name Type
  protein HydH protein
  protein ZraP protein
  protein ZraR protein
  complex ZraR-phosphate complex
  protein ZraS protein
  simple_molecule phosphate simple_molecule
  gene zraP gene
  RNA zraP_mRNA RNA
  gene zraSR gene
  RNA zraSR_mRNA RNA


Reactions       
Showing 7 reactions
phosphate + ZraR ZraR-phosphate
Name: phosphate + ZraR -> ZraR-phosphate
Description: Reaction transforming phosphate, ZraR into ZraR-phosphate
Type: state transition
Pathway Components: phosphate + ZraR -> ZraR-phosphate
Components:
Function Name Type
reactant ZraR protein
product ZraR-phosphate complex
reactant phosphate simple_molecule
ZraR-phosphate zraP zraP_mRNA
Name: zraP -> zraP_mRNA
Description: Transcription of transcription unit zraP. Reaction activation by ZraR-phosphate.
Type: transcription
Pathway Components: zraP - ZraR-phosphate -> zraP_mRNA
Components:
Function Name Type
activator ZraR-phosphate complex
reactant zraP gene
product zraP_mRNA RNA
ZraR-phosphate zraSR zraSR_mRNA
Name: zraSR -> zraSR_mRNA
Description: Transcription of transcription unit zraSR. Reaction activation by ZraR-phosphate.
Type: transcription
Pathway Components: zraSR - ZraR-phosphate -> zraSR_mRNA
Components:
Function Name Type
activator ZraR-phosphate complex
reactant zraSR gene
product zraSR_mRNA RNA
zraP_mRNA ZraP
Name: zraP_mRNA -> ZraP
Description: Translation of ZraP
Type: translation
Pathway Components: zraP_mRNA -> ZraP
Components:
Function Name Type
product ZraP protein
reactant zraP_mRNA RNA
zraSR_mRNA ZraS
Name: zraSR_mRNA -> ZraS
Description: Translation of ZraS
Type: translation
Pathway Components: zraSR_mRNA -> ZraS
Components:
Function Name Type
product ZraS protein
reactant zraSR_mRNA RNA
zraSR_mRNA HydH
Name: zraSR_mRNA -> HydH
Description: Translation of HydH
Type: translation
Pathway Components: zraSR_mRNA -> HydH
Components:
Function Name Type
product HydH protein
reactant zraSR_mRNA RNA
zraSR_mRNA ZraR
Name: zraSR_mRNA -> ZraR
Description: Translation of ZraR
Type: translation
Pathway Components: zraSR_mRNA -> ZraR
Components:
Function Name Type
product ZraR protein
reactant zraSR_mRNA RNA
R1 R2 R3 R4 R5 R6 R7



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