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TorR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
TorR pyruvate TMAO torR gadAX a-reduced-TorC-protein YhiD TnaB TorA L-glutamate an-oxidized-TorC-protein TorR torCAD gadAX_mRNA TorA TorI TorC GadA CO2 HdeB TnaC vitamin K2 cysteine torR_mRNA phosphate tnaC TorR ammonium HdeA dehydroalanine TorC hdeAB-yhiD_mRNA hdeAB-yhiD (CH3)3NH torCAD_mRNA tnaC_mRNA sulfide tnaCAB phosphate GABA tryptophan menaquinol tnaCAB_mRNA TorI GadX TnaA TorD tryptophan_Ext indole


Gensor Unit       
Name: TorR
Signal name: trimethylamine N-oxide (TMAO).
Classification:
Groups: Posttranslational modification, protein turnover, chaperones
Transcription
Energy production and conversion
Signal transduction mechanisms
Amino acid transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0009060 - aerobic respiration
GO:0003333 - amino acid transmembrane transport
GO:0006865 - amino acid transport
GO:0019645 - anaerobic electron transport chain
GO:0009061 - anaerobic respiration
GO:0009072 - aromatic amino acid family metabolic process
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cellular_component GO:0009276 - Gram-negative-bacterium-type cell wall
GO:0060187 - cell pole
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
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molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0080146 - L-cysteine desulfhydrase activity
GO:0015173 - aromatic amino acid transmembrane transporter activity
GO:0016830 - carbon-carbon lyase activity
GO:0016831 - carboxy-lyase activity
GO:0003824 - catalytic activity
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Components:
  Function Name Type
  simple_molecule (CH3)3NH simple_molecule
  simple_molecule CO2 simple_molecule
  simple_molecule GABA simple_molecule
  protein GadA protein
  protein GadX protein
  protein HdeA protein
  protein HdeB protein
  simple_molecule L-glutamate simple_molecule
  simple_molecule TMAO simple_molecule
  protein TnaA protein
  protein TnaB protein
  protein TnaC protein
  protein TorA protein
  protein TorC protein
  complex TorC-TorA complex
  protein TorD protein
  protein TorI protein
  protein TorR protein
  complex TorR-TorI complex
  complex TorR-phosphate complex
  protein YhiD protein
  simple_molecule a-reduced-TorC-protein simple_molecule
  simple_molecule ammonium simple_molecule
  simple_molecule an-oxidized-TorC-protein simple_molecule
  simple_molecule cysteine simple_molecule
  simple_molecule dehydroalanine simple_molecule
  gene gadAX gene
  RNA gadAX_mRNA RNA
  gene hdeAB-yhiD gene
  RNA hdeAB-yhiD_mRNA RNA
  simple_molecule indole simple_molecule
  simple_molecule menaquinol simple_molecule
  simple_molecule phosphate simple_molecule
  simple_molecule pyruvate simple_molecule
  simple_molecule sulfide simple_molecule
  gene tnaC gene
  gene tnaCAB gene
  RNA tnaCAB_mRNA RNA
  RNA tnaC_mRNA RNA
  gene torCAD gene
  RNA torCAD_mRNA RNA
  gene torR gene
  RNA torR_mRNA RNA
  simple_molecule tryptophan simple_molecule
  simple_molecule tryptophan_Ext simple_molecule
  simple_molecule vitamin K2 simple_molecule


Reactions       
Showing 30 reactions
phosphate + TorR TorR-phosphate
Name: phosphate + TorR -> TorR-phosphate
Description: Reaction transforming phosphate, TorR into TorR-phosphate
Type: state transition
Pathway Components: phosphate + TorR -> TorR-phosphate
Components:
Function Name Type
reactant TorR protein
product TorR-phosphate complex
reactant phosphate simple_molecule
TorR-phosphate tnaC tnaC_mRNA
Name: tnaC -> tnaC_mRNA
Description: Transcription of transcription unit tnaC. Reaction activation by TorR-phosphate.
Type: transcription
Pathway Components: tnaC - TorR-phosphate -> tnaC_mRNA
Components:
Function Name Type
activator TorR-phosphate complex
reactant tnaC gene
product tnaC_mRNA RNA
TorR-phosphate tnaCAB tnaCAB_mRNA
Name: tnaCAB -> tnaCAB_mRNA
Description: Transcription of transcription unit tnaCAB. Reaction activation by TorR-phosphate.
Type: transcription
Pathway Components: tnaCAB - TorR-phosphate -> tnaCAB_mRNA
Components:
Function Name Type
activator TorR-phosphate complex
reactant tnaCAB gene
product tnaCAB_mRNA RNA
TorR-phosphate torCAD torCAD_mRNA
Name: torCAD -> torCAD_mRNA
Description: Transcription of transcription unit torCAD. Reaction activation by TorR-phosphate.
Type: transcription
Pathway Components: torCAD - TorR-phosphate -> torCAD_mRNA
Components:
Function Name Type
activator TorR-phosphate complex
reactant torCAD gene
product torCAD_mRNA RNA
TorR-phosphate torR torR_mRNA
Name: torR -> torR_mRNA
Description: Transcription of transcription unit torR. Reaction inhibition by TorR-phosphate.
Type: transcription
Pathway Components: torR - TorR-phosphate -> torR_mRNA
Components:
Function Name Type
inhibitor TorR-phosphate complex
reactant torR gene
product torR_mRNA RNA
TorI + TorR TorR-TorI
Name: TorI + TorR -> TorR-TorI
Description: Reaction transforming TorI, TorR into TorR-TorI
Type: state transition
Pathway Components: TorI + TorR -> TorR-TorI
Components:
Function Name Type
reactant TorI protein
reactant TorR protein
product TorR-TorI complex
TorR-TorI hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD. Reaction activation by TorR-TorI.
Type: transcription
Pathway Components: hdeAB-yhiD - TorR-TorI -> hdeAB-yhiD_mRNA
Components:
Function Name Type
activator TorR-TorI complex
reactant hdeAB-yhiD gene
product hdeAB-yhiD_mRNA RNA
TorR-TorI gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX. Reaction inhibition by TorR-TorI.
Type: transcription
Pathway Components: gadAX - TorR-TorI -> gadAX_mRNA
Components:
Function Name Type
inhibitor TorR-TorI complex
reactant gadAX gene
product gadAX_mRNA RNA
torR_mRNA TorR
Name: torR_mRNA -> TorR
Description: Translation of TorR
Type: translation
Pathway Components: torR_mRNA -> TorR
Components:
Function Name Type
product TorR protein
reactant torR_mRNA RNA
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Pathway Components: gadAX_mRNA -> GadA
Components:
Function Name Type
product GadA protein
reactant gadAX_mRNA RNA
GadA L-glutamate GABA + CO2
Name: L-glutamate -> GABA + CO2
Description: Reaction transforming L-glutamate into GABA, CO2
Type: state transition
Pathway Components: L-glutamate - GadA -> GABA + CO2
Components:
Function Name Type
product CO2 simple_molecule
product GABA simple_molecule
catalyzer GadA protein
reactant L-glutamate simple_molecule
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadAX_mRNA -> GadX
Components:
Function Name Type
product GadX protein
reactant gadAX_mRNA RNA
tnaCAB_mRNA TnaC
Name: tnaCAB_mRNA -> TnaC
Description: Translation of TnaC
Type: translation
Pathway Components: tnaCAB_mRNA -> TnaC
Components:
Function Name Type
product TnaC protein
reactant tnaCAB_mRNA RNA
tnaCAB_mRNA TnaA
Name: tnaCAB_mRNA -> TnaA
Description: Translation of TnaA
Type: translation
Pathway Components: tnaCAB_mRNA -> TnaA
Components:
Function Name Type
product TnaA protein
reactant tnaCAB_mRNA RNA
TnaA ammonium tryptophan pyruvate + ammonium + indole
Name: tryptophan -> pyruvate + ammonium + indole
Description: Reaction transforming tryptophan into pyruvate, ammonium , indole
Type: state transition
Pathway Components: tryptophan - TnaA - ammonium -> pyruvate + ammonium + indole
Components:
Function Name Type
catalyzer TnaA protein
inhibitor ammonium simple_molecule
product ammonium simple_molecule
product indole simple_molecule
product pyruvate simple_molecule
reactant tryptophan simple_molecule
TnaA tryptophan dehydroalanine + indole
Name: tryptophan -> dehydroalanine + indole
Description: Reaction transforming tryptophan into dehydroalanine, indole
Type: state transition
Pathway Components: tryptophan - TnaA -> dehydroalanine + indole
Components:
Function Name Type
catalyzer TnaA protein
product dehydroalanine simple_molecule
product indole simple_molecule
reactant tryptophan simple_molecule
TnaA cysteine ammonium + pyruvate + sulfide
Name: cysteine -> ammonium + pyruvate + sulfide
Description: Reaction transforming cysteine into ammonium, pyruvate , sulfide
Type: state transition
Pathway Components: cysteine - TnaA -> ammonium + pyruvate + sulfide
Components:
Function Name Type
catalyzer TnaA protein
product ammonium simple_molecule
reactant cysteine simple_molecule
product pyruvate simple_molecule
product sulfide simple_molecule
TnaA cysteine dehydroalanine + sulfide
Name: cysteine -> dehydroalanine + sulfide
Description: Reaction transforming cysteine into dehydroalanine, sulfide
Type: state transition
Pathway Components: cysteine - TnaA -> dehydroalanine + sulfide
Components:
Function Name Type
catalyzer TnaA protein
reactant cysteine simple_molecule
product dehydroalanine simple_molecule
product sulfide simple_molecule
tnaCAB_mRNA TnaB
Name: tnaCAB_mRNA -> TnaB
Description: Translation of TnaB
Type: translation
Pathway Components: tnaCAB_mRNA -> TnaB
Components:
Function Name Type
product TnaB protein
reactant tnaCAB_mRNA RNA
TnaB tryptophan_Ext tryptophan
Name: tryptophan_Ext -> tryptophan
Description: Transport of tryptophan_Ext through a bacterial membrane, leading to the presence of tryptophan inside the cell.
Type: transport
Pathway Components: tryptophan_Ext - TnaB -> tryptophan
Components:
Function Name Type
catalyzer TnaB protein
product tryptophan simple_molecule
reactant tryptophan_Ext simple_molecule
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeA
Components:
Function Name Type
product HdeA protein
reactant hdeAB-yhiD_mRNA RNA
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeB
Components:
Function Name Type
product HdeB protein
reactant hdeAB-yhiD_mRNA RNA
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> YhiD
Components:
Function Name Type
product YhiD protein
reactant hdeAB-yhiD_mRNA RNA
tnaC_mRNA TnaC
Name: tnaC_mRNA -> TnaC
Description: Translation of TnaC
Type: translation
Pathway Components: tnaC_mRNA -> TnaC
Components:
Function Name Type
product TnaC protein
reactant tnaC_mRNA RNA
torCAD_mRNA TorC
Name: torCAD_mRNA -> TorC
Description: Translation of TorC
Type: translation
Pathway Components: torCAD_mRNA -> TorC
Components:
Function Name Type
product TorC protein
reactant torCAD_mRNA RNA
TorA + TorC TorC-TorA
Name: TorA + TorC -> TorC-TorA
Description: Reaction transforming TorA, TorC into TorC-TorA
Type: state transition
Pathway Components: TorA + TorC -> TorC-TorA
Components:
Function Name Type
reactant TorA protein
reactant TorC protein
product TorC-TorA complex
TorC-TorA menaquinol + TMAO vitamin K2 + (CH3)3NH
Name: menaquinol + TMAO -> vitamin K2 + (CH3)3NH
Description: Reaction transforming menaquinol, TMAO into vitamin K2, (CH3)3NH
Type: state transition
Pathway Components: menaquinol + TMAO - TorC-TorA -> vitamin K2 + (CH3)3NH
Components:
Function Name Type
product (CH3)3NH simple_molecule
reactant TMAO simple_molecule
catalyzer TorC-TorA complex
reactant menaquinol simple_molecule
product vitamin K2 simple_molecule
torCAD_mRNA TorA
Name: torCAD_mRNA -> TorA
Description: Translation of TorA
Type: translation
Pathway Components: torCAD_mRNA -> TorA
Components:
Function Name Type
product TorA protein
reactant torCAD_mRNA RNA
TorA a-reduced-TorC-protein + TMAO an-oxidized-TorC-protein + (CH3)3NH
Name: a-reduced-TorC-protein + TMAO -> an-oxidized-TorC-protein + (CH3)3NH
Description: Reaction transforming a-reduced-TorC-protein, TMAO into an-oxidized-TorC-protein, (CH3)3NH
Type: state transition
Pathway Components: a-reduced-TorC-protein + TMAO - TorA -> an-oxidized-TorC-protein + (CH3)3NH
Components:
Function Name Type
product (CH3)3NH simple_molecule
reactant TMAO simple_molecule
catalyzer TorA protein
reactant a-reduced-TorC-protein simple_molecule
product an-oxidized-TorC-protein simple_molecule
torCAD_mRNA TorD
Name: torCAD_mRNA -> TorD
Description: Translation of TorD
Type: translation
Pathway Components: torCAD_mRNA -> TorD
Components:
Function Name Type
product TorD protein
reactant torCAD_mRNA RNA
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